ANALISA HIDROKUINON DALAM KRIM DOKTER SECARA SPEKTROFOTOMETRI UV-VIS
DOI:
https://doi.org/10.22373/lj.v6i2.3517Keywords:
Cream, Hydroquinone, UV-Vis Spectrophotometry.Abstract
Cosmetics is products used to enhance the appearance of face. Various kinds of cosmetic products are increasingly emerging at this time. One kind of cosmetic is whitening cream. The whitening cream contains of an active substance used to tint black spots on the skin. The active substance which often used in cosmetics is hydroquinone. Hydroquinone is a class of hard drugs whose use must be based on a doctor's prescription. The use of hydroquinone is prohibited on cosmetic preparations that are sold freely, but may be used if under the supervision of a physician 2% (BPOM, 2007). The aim of this study was to determine the existence and level of hydroquinone in whitening cream. The results of the analysis showed that samples A, B, C, D, E, F, H and I were positive for hydroquinone with percentage of hydroquinone was about 0.000168%, 0.000319%, 0.000309%, 0.001188%, 0.00392%, 0.000058%, 0.000521%, 0.000899%, whereas the G sample was not detected.References
Aryani, N. L. D., Khesuma, D., dan Khosasi, W, 2010, Pemeriksaan Hidrokuinon dengan Spektrofotometri dalam Sediaan Krim Pencerah Kulit N, DL dan NNN, Fakultas Farmasi, Universitas Surabaya, Seminar Teknik Kimia, Soehadi Reksowardjo.
Badan Pengawas Obat dan Makanan. 2007. Keputusan Kepala Badan Pengawas Obat dan Makanan Republik Indonesia No.KH.00.01.432.6081 tentang Kosmetik Mengandung Bahan Berbahaya dan Zat Warna yang Dilarang. Jakarta.
Gandjar., I. G., dan Rohman, A., 2007, Kimia Farmasi Analisis, Yogyakarta: Pustaka Pelajar.
Gianti, 2013, Analisis Kandungan Merkuri dan Hidrokuinon Dalam Kosmetik Krim Racikan Dokter, Skripsi, Jakarta: Fakultas Kedokteran dan Ilmu Kesehatan UIN Syarif Hidayatullah.
Ibrahim, S., Damayanti, S., Riani, Y., 2004. Penetapan Kecermatan dan Keseksamaan Metode Kalorimetri Menggunakan Pereaksi Floroglusin untuk Penetapan Kadar Hidrokuinon dalam Krim Pemucat. Act Pharm, 29 (1): 28-33.
Irnawati, Sahumena, M.H., dan Dewi, W. O., 2016, Analisis Hidrokuinon pada Krim Pemutih Wajah dengan Menggunakan Spektrofotometri UV-Vis. Jurnal Ilmiah Farmasi UNSRAT: Pharmacon. 5 (3): 2302-2493.
Miller, J. N., dan Miller J. C., 2010, Statistics And Chemometries For Analytical Chemistry. Sixth Edition. England: Pearson Education.
Prabawati, I. D. A., Fatimawali, Yudistira, A., 2012, Analisis Zat Hidrokuinon pada Krim Pemutih Wajah yang Beredar di Kota Manado. Jurnal Ilmiah Farmasi UNSRAT: Pharmacon. 1(1): 41-46.
Sastrohamidjojo, H, 2001, Spektroskopi, Yogyakarta: Liberty.
Sarah, K, W, 2014, Analisis Hidrokuinon dalam Sediaan Krim malam “CW1” dan “CW2” dari Klinik Kecantikan “N” dan “E” di Kabupaten Sidoharjo, Jurnal Ilmiah Mahasiswa Universitas Surabaya, 3(2).
Trangono R. I., dan Latifah F., 2013, Buku Pegangan Ilmu Pengetahuan Kosmetik. Jakarta: Gramedia.
Downloads
Published
Issue
Section
License
Proposed Policy for Journals That Offer Open Access Authors who publish with Lantanida Journal agree to the following terms: a. Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal. b. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal. c. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).
